Jonathan Dornell, PhD

The State of Prebiotics, Probiotics, and Postbiotics in Oral Health

Title

The State of Prebiotics, Probiotics, and Postbiotics in Oral Health

Presented By

Jonathan Dornell, PhD

Let's Get Oral

Presentation Time

3:00-3:30PM

Abstract

In recent years, there has been an emerging conversation within oral care: should we move away from targeting harmful bacteria towards fostering a balanced oral microbiome? A lot of these conversations are fueled by growing interest in the use of prebiotics, probiotics, and postbiotics as oral care applications. Prebiotics, probiotics, and postbiotics represent a promising approach to promoting oral health by modulating the oral microbiome. Several clinical studies have investigated the efficacy of prebiotics, probiotics, and postbiotics in treating chronic diseases such as dental caries and periodontitis. While some studies have reported positive outcomes, others have yielded mixed results. Factors such as the choice of active ingredient(s), dosage, delivery methods, and individual variability are some of the variables that may influence the effectiveness of these biotics. Additionally, further research is needed to optimize their use and establish clear guidelines for their integration into routine oral care practices.

Meet the Speaker

Jonathan Dornell is an entrepreneurial biochemist and microbial ecologist dedicated to the advancement of personalized health technologies. With an original interest in practicing dentistry, Jonathan instead indulged his curiosity about the oral microbiome by focusing his doctoral research on understanding the ecological interactions between the opportunistic pathogen Candida albicans and oral bacteria found in plaque-forming biofilms. This training experience laid the foundation of his personal and professional journey to help society better understand the role of the microbiome in oral health and nature.

Jonathan earned his undergraduate degrees in Biology and Philosphy from Florida State University and his doctoral degree from Rice University in the Biosciences Department. Today, he splits his time between helping clients understand how to effectively use microorganisms in their business and producing Let’s Get Oral, an educational podcast that spreads awareness of emerging oral care insights. His skillset blends a deep knowledge of cell biology, biochemistry, and microbiology with product development experience in biologics, dietary supplements, and functional foods